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  • Ming-Long Wu

    Ming-Long WuAssociate Professor

    Contact Info.

    Department: dept. CSIE / inst. CSIE / IMI / AI Program

    Tel: 06-2757575 ext 62541

    E-mail: minglong.wu@csie.ncku.edu.tw

    Lab: Biomedical Imaging Laboratory (65902, 9F, CSIE new building)

    Research Interests

    Deep learning、Data science、Biomedical image processing、Magnetic Resonance Imaging, MRI、Functional MRI、MRI pulse sequence design、Machine learning

    School Record

    Taiwan \ National Taiwan University \ Electrical Engineering \ Ph.D(2001 ~ 2006)

    Taiwan \ National Taiwan University \ Electrical Engineering \ M.S.(1998 ~ 2000)

    United States \ Harvard University \ Computational Science and Eng. \ M.S.(2016 ~ 2017)

    Taiwan \ National Taiwan University \ Electrical Engineering \ B.S.(1994 ~ 1998)

    Record

    National Cheng Kung University \ Mind Research and Imaging (MRI) Center \ Technical team leader (2010 ~ now)

    International Society for Magnetic Resonance in Medicine (ISMRM) \ \ Member (0000 ~ now)

    Association for Computing Machinery (ACM) \ \ Member (0000 ~ now)

    Institute of Electrical and Electronics Engineers (IEEE) \ \ Senior member (0000 ~ now)

    Duke University Medical Center \ Brain Imaging and Analysis Center \ Postdoctoral Associate (2008 ~ 2010)

    Harvard Medical School \ Brigham and Women's Hospital \ Postdoctoral Research Fellow (2006 ~ 2008)

    Honor & Awards

    2020 NCKU Outstanding Teaching Excellence Award

    2007 Taiwan Merit Scholarship, National Science Council

    2005 Student stipend award, ISMRM

    2003 Student stipend award, ISMRM

    2000 Student stipend award, ISMRM

    Publications

    Refereed Papers

    1. M-L. Wu, C-K. Wang, P-Y. Lin, T-C. Chao "Optimization of quantitative susceptibility mapping by streaking artifact detection" Medical PhysicsMOST 104-2221-E-006 -266 -MY2SCI

    2. S-C. Chiu, H-C. Chang, M-L. Chu, M-L. Wu, H-W. Chung, Y-R. Lin "De-aliasing for signal restoration in Propeller MR imaging" Magnetic Resonance Imaging, 36(2): 12-15MOST 104-2221-E-006-266-MY2SCI

    3. M-L. Wu, H-C. Chang, T-C. Chao, N-K. Chen "Efficient imaging of midbrain nuclei using inverse double-echo steady-state acquisition" Medical Physics, 42(7):4367-4374, Jul 2015SCI

    4. P-Y. Lin, T-C. Chao, M-L. Wu "Quantitative Susceptibility Mapping of Human Brain at 3 Tesla: A Multisite Reproducibility Study" American Journal of Neuroradiology, 36: 467-474, Mar 2015SCI

    5. P-H. Wu, C-C. Cheng, M-L. Wu, T-C. Chao, H-W. Chung, and T-Y. Huang "Effects of RF profile on precision of quantitative T2 mapping using dual-echo steady-state acquisition" Magnetic Resonance Imaging, 32(1):102-6, Jan 2014SCI

    6. P-H. Wu, P-H. Tsai, M-L. Wu, T-C. Chuang, Y-Y. Shih, H-W. Chung, and T-Y. Huang "High spatial resolution brain functional MRI using submillimeter balanced steady-state free precession acquisition" Medical Physics, 40(12):122304, Dec 2013SCI

    7. Y-J. Liu, C-J. Juan, C-Y. Chen, C-Y. Wang, M-L. Wu, C-P. Lo, M-C. Chou, T-Y. Huang, H. Chang, C-H. Chu, and M-H. Li "Are the local blood oxygen level-dependent (BOLD) signals caused by neural stimulation response dependent on global BOLD signals induced by hypercapnia in the functional MR imaging experiment? Experiments of long-duration hypercapnia and multilevel carbon dioxide concentration." American Journal of Neuroradiology, 28(6):1009-14, Jun 2007SCI

    8. M-L. Wu, P-H. Wu, T-Y. Huang, Y-Y. Shih, M-C. Chou, H-S. Liu, H-W. Chung, and C-Y. Chen "Frequency Stabilization Using Infinite Impulse Response Filtering for BOSS fMRI at 3T" Magnetic Resonance in Medicine, 57:369-379, Feb 2007SCI

    9. M-C. Chou, M-L. Wu, C-Y. Chen, C-Y Wang, T-Y. Huang, Y-J. Liu, C-J. Juan, and H-W. Chung "TENsor Deflection (TEND) Tractography with Adaptive Sub-voxel Stepping" Journal of Magnetic Resonance Imaging, 24:451-458, Aug 2006SCI

    10. K-H. Chuang, M-T. Wu, Y-R. Lin, K-S. Hsieh, M-L. Wu, S-Y. Tsai, C-W. Ko, and H-W. Chung "Application of model-free analysis in the MR assessment of pulmonary perfusion dynamics" Magnetic Resonance in Medicine 54(2):299-308, Aug 2005SCI

    11. M-L. Wu, C-W. Ko, T-Y. Chen, M-T. Wu, H-W. Chung, T-Y. Huang, and Y-R. Lin "MR Ventriculocisternography By Using 3D Balanced Steady-State Free Precession Imaging: Technical Note" American Journal of Neuroradiology, 26:1170-1173, May 2005SCI

    12. W-C. Wu, C-C. Huang, H-W. Chung, M. Liou, C-J. Hsueh, C-S. Lee, M-L. Wu, and C-Y. Chen "Hippocampal Alterations in Children with Temporal Lobe Epilepsy with or without a History of Febrile Convulsions: Evaluations with MR Volumetry and Proton MR Spectroscopy" American Journal of Neuroradiology, 26:1270-1275, May 2005SCI

    Conference Papers

    International Conference

    1. T-C. Chao, T-H. Lin, M-L. Wu "A Cascade Deep Network to Improve Parallel MRI Reconstruction" AAPM 61th meeting, San Antonio, Texas, USA 2019MOST 107-2221-E-006-075-MY2

    2. C-C. Tsai, T-C. Chao, M-H. Ho, Y-J. Liu, M-L. Wu "Thin Slab Cerebral Quantitative Susceptibility Mapping" ISMRM 26th meeting, Paris, France 2018MOST 106-2221-E-006-068-

    3. T-L. Wu, C-L. Cheng, M-T. Wu, M-L. Wu, T-C. Chao "Accelerated Free Breathing Cardiac Cine Imaging with PROPELLER and GRAPPA" ISMRM 23th meeting, Toronto, Canada 2015

    4. Y-L. Li, T-C. Chao, M-L. Wu "Analyzing Brain Networks in Motor fMRI Using Anatomically Weighted Functional Connectivity" IFMIA, Tainan, Taiwan 2015

    5. I-J. Chen, Y-H. Cheng, T-C. Chao, M-L. Wu "Effects of Temporal Resolution on Granger Causality Analysis in Auditory-Motor fMRI" ISMRM 22th meeting, Milan, Italy 2014

    6. C-K. Wang, P-Y. Lin, T-C. Chao, M-L. Wu "Automatic Artifact Detection and Image Quality Assessment for Quantitative Susceptibility Mapping" ISMRM 22th meeting, Milan, Italy 2014

    7. Y-H. Cheng, I-J. Chen, T-C. Chao, M-L. Wu "Evaluating Effective Connectivity in Auditory-Motor fMRI Using Dynamic Granger Causality Analysis" ISMRM 22th meeting, Milan, Italy 2014

    8. Y-L. Wu, S-M. Huang, S-L. Peng, Y-C. Wu, T-C. Yang, J-C. Hsu, M-L. Wu, F-N. Wang "Resting State Network in ADHD Rat Model Using Group ICA" ISMRM 21th meeting, Salt Lake City, USA 2013

    9. P-H. Wu, C-W. Ko, M-L. Wu, and H-W. Chung "Effects of Flip Angle Profile in T2 Quantification Using 3D Dual Echo Steady-State (DESS)" ISMRM 21th meeting, Salt Lake City, USA 2013

    10. I-J. Chen, Y-H. Cheng, T-C. Chao, P-H. Lai, F-N. Wang, and M-L. Wu "Effective Brain Connectivity Among Resting-State Networks: A Frequency Dependent Granger Causality Analysis" ISMRM 21th meeting, Salt Lake City, USA 2013

    11. S-F. Liang, T-H. Hsieh, P-Z. Chen, M-L. Wu, C-C. Kung, C-Y. Lin, F-Z. Shaw "Differentiation between resting-state fMRI data from ADHD and normal subjects: Based on functional connectivity and machine learning" Fuzzy Theory and it's Applications (iFUZZY), International Conference on, pp.294,298, 2012

    12. C-J. Juan, Y-J. Liu, Y-H. Lee, T-Y. Huang, F-N. Wang, M-L. Wu "To Investigate the Cerebral Vasomotor Reactivity by CO2 Stimulus Using Cine PCMRI" ISMRM 20th meeting, Melbourne, Australia 2012

    13. H-C. Chang, N-K. Chen, T-C. Chuang, C-J. Juan, M-L. Wu, H-W. Chung "PROPELLER-EPI improved by 2D phase cycled reconstruction" ISMRM 20th meeting, Melbourne, Australia 2012

    14. M-L. Wu, H-C. Chang, T-C. Chao, P-H. Wu, and N-K. Chen "Midbrain nuclei visualization improved by susceptibility-enhanced 3D inversed Double Echo Steady State (iDESS) imaging" ISMRM 20th meeting, Melbourne, Australia 2012

    15. P-H. Wu, H-W. Chung, M-L. Wu, T-C. Chuang, T-C. Chao "Brain fMRI with dual echo steady-state (DESS) imaging: preliminary findings on signal behavior and flip-angle dependency" ISMRM 20th meeting, Melbourne, Australia 2012

    16. Y-W. Tang, T-Y. Huang, M-L. Wu, C-W. Ko "An automatic real-time feedback calibration of RF phase cycling by off-resonance weighted imaging sequence" ISMRM 20th meeting, Melbourne, Australia 2012

    17. M-L. Wu, and N-K. Chen "Midbrain Nuclei Visualization Improved by Susceptibility-enhanced 3D Multi-echo SSFP for Deep Brain Stimulation Guidance" ISMRM 18th meeting, Stockholm, Sweden 2010

    18. M-L. Wu, and N-K. Chen "Artifact-free and Multi-contrast SSFP Imaging Achieved in a Single Acquisition" ISMRM 17th meeting, Hawaii, USA 2009

    19. T-C. Chao, B. Madore, M-L. Wu, J. Yuan, and H-W. Chung "Incorporating Self-Referenced Information Into Compressed Sensing in Dynamic Imaging" ISMRM 17th meeting, Hawaii, USA 2009

    20. O. Afacan, W.S. Hoge, D.H. Brooks, J. Yuan, M-L. Wu, L.P. Panych, and I.A. Morocz "A Method to Increase Temporal Resolution in 3D-EPI fMRI Using UNFOLD" ISMRM 17th meeting, Hawaii, USA 2009

    21. M-L. Wu, L.P. Panych, and N-K. Chen "Optimizing 3D EPI with k-space Energy Spectrum Analysis (KESA)" ISMRM 16th meeting, Toronto, Canada 2008

    22. P-H. Wu, T-Y. Huang, M-L. Wu, H-S. Liu, H-W. Chung, and C-Y. Chen "Transition-Band SSFP fMRI with Increased Spatial Coverage: Slice-Dependent Frequency Adjustments in a Bilateral Motor Activation Experiment" ISMRM 16th meeting, Toronto, Canada 2008

    23. P-H. Wu, T-Y. Huang, M-L. Wu, H-S. Liu, H-W. Chung, and C-Y. Chen "Improvements in Sweep Scans for Frequency Adjustments in SSFP fMRI Using Coarse Sampling with Cubic Spline Interpolation" ISMRM 16th meeting, Toronto, Canada 2008

    24. M-L. Wu, P-H. Wu, T-Y. Huang, Y-Y. Shih, M-C. Chou, H-S. Liu, H-W. Chung, and C-Y. Chen "SSFP fMRI at 0.37 mm3 Voxel Volume: Effects of Spatial Resolution on SNR and Functional Sensitivity" ISMRM 15th meeting, Berlin, Germany 2007

    25. M-L. Wu, T-Y. Huang, P-H. Wu, Y-Y. Shih, M-C. Chou, H-S. Liu, H-W. Chung, and C-Y. Chen "Automatic Slice-dependent Frequency Adjustments for SSFP fMRI" ISMRM 15th meeting, Berlin, Germany 2007

    26. P-H. Wu, M-L. Wu, T-Y. Huang, and H-W. Chung "SSFP fMRI with Parallel Interleaved Multiple Frequency Acquisition" ISMRM 15th meeting, Berlin, Germany 2007

    27. M-L. Wu, T-Y. Huang, P-H. Wu, M-C. Chou, C-Y. Chen, and H-W. Chung "Frequency Stabilization Using Finite Impulse Response Filtering for BOSS fMRI at 3T" ISMRM 14th meeting, Seattle, USA 2006

    28. P-H. Wu, M-L. Wu, T-Y. Huang, and H-W. Chung "Transient State BOSS fMRI for a Further Increase in Sensitivity" ISMRM 14th meeting, Seattle, USA 2006

    29. M-C. Chou, H-W. Chung, T-Y. Huang, H-S. Liu, C-Y. Wang, M-L. Wu, and C-Y. Chen "Q-Ball Imaging with PROPELLER Acceleration" ISMRM 14th meeting, Seattle, USA 2006

    30. Y-R. Lin, S-Y. Tsai, T-Y. Huang, M-L. Wu, C-Y. Chen, H-W. Chung, N-K. Chen and K. Kwong "Double-Sampled EPI in fMRI: A Ghost-Free Acquisition Method with Inherent Field Map Correction Capability" ISMRM 14th meeting, Seattle, USA 2006

    31. M-L. Wu, Y-J. Liu, M-C. Chung, K-H. Chuang, H-W. Chung, and C-Y. Chen "Cascaded ICA-clustering Networks for MRI Analysis: Preliminary Results from Brain Perfusion Images" ESMRMB 22th meeting, Basel, Switzerland 2005

    32. M-L. Wu, Y-J. Liu, C-J. Juan, H-W. Chung, and C-Y. Chen "Bayesian Component Number Estimation while Applying ICA to Functional MRI" ISMRM 13th meeting, Miami, USA 2005

    33. M-C. Chou, M-L. Wu, H-W. Chung, C-Y. Wang, and C-Y. Chen "TENsor Deflection (TEND) Tractography with Sub-pixel Adaptive Step Size" ISMRM 13th meeting, Miami, USA 2005

    34. M-L. Wu, S-Y. Tsai, Y-R. Lin, T-Y. Huang, M-T. Wu, H-W. Chung, C-Y. Chen, and H-B. Pan "MR Dynamic Contrast Pulmonary Images Analyzed by Independent Component Analysis: More Accurate Assessment of Pulmonary Perfusion" ISMRM 11th meeting, Toronto, Canada 2003

    35. K-H. Chuang, M-T. Wu, H-W. Chung, M-L. Wu, and S-Y. Tsai "Novel Application of Model-free Analysis in the MR Assessment of Pulmonary Perfusion Dynamics" ISMRM 11th meeting, Toronto, Canada 2003

    36. M-L. Wu, W-C. Wu, C-W. Ko, C-Y. Chen, and H-W. Chung "Angiogenesis in Cerebral Gliomas: T2* rCBV Map Versus Pathological Vascularity" ISMRM 8th meeting, Denver, USA 2000

    37. M-L. Wu, W-C. Wu, H-W. Chung, and C-Y. Chen "A Simple Efficient Algorithm for Brain Segmentation on T1-weighted Images Employing Edge Detection" ISMRM 8th meeting, Denver, USA 2000

    38. W-C. Wu, M-L. Wu, C-W. Ko, C-Y. Chen, and H-W. Chung "Comparison of Volumetry and Proton MRS in Hippocampi of Children with History of Febrile Convulsion and/or Temporal Lobe Epilepsy" ISMRM 8th meeting, Denver, USA 2000

    39. W-C. Wu, M-L. Wu, C-W. Ko, C-Y. Chen, and H-W. Chung "Regional Discrepancy of Apparent Diffusion Coefficient in Cerebral Gliomas: Correlation with Tumor rCBV and CSI" ISMRM 8th meeting, Denver, USA 2000

    40. C-W. Ko, W-C. Wu, M-L. Wu, C-Y. Chen, and H-W. Chung "Preoperative Differentiation of Benign from Malignant Cerebral Glioma using Perfusion EPI and CSI: Preliminary Results" ISMRM 8th meeting, Denver, USA 2000

    National Conference

    1. T-Y. Huang, M-L. Wu, Y-D. Lin, and H-W. Chung "Implementation of Fax-ECG System" Annual Symposium of the Biomedical Engineering Society, Taipei, R.O.C. 1998

    Projects

    National Science Council Projects

    Project Name Since Sponsor
    Quantitative Susceptibility Mapping with artificial intelligence techniques2021 ~ 2024Ministry of Science and Technology
    Magnetic resonance brain tumor automatic tissue segmentation system achieved by efficient deep learning2018 ~ 2020Ministry of Science and Technology
    Development of a functional MRI neurofeedback platform: application to memory training2017 ~ 2018Ministry of Science and Technology
    Magnetic Resonance Quantitative Susceptibility Mapping in human brain: technical development of a biomarker for neuronal diseases2015 ~ 2017Ministry of Science and Technology
    Midbrain Imaging Improved by Susceptibility Weighted Image and 3D Double-echo Steady State Free Precession Imaging: Targeting at Parkinson\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'s Disease2012 ~ 2014National Science Council
    High resolution and high contrast imaging in subthalamus using multi-echo Steady-state Free Precession imaging (Part-II)2011 ~ 2012National Science Council
    High resolution and high contrast imaging in subthalamus using multi-echo Steady-state Free Precession imaging (Part-I)2011 ~ 2011National Science Council

    General Projects

    Project Name Since Sponsor
    Feasibility Study for Automatic Screening of Developmental Dysplasia of the Hip2021 ~ 2021MIRDC
    Feasibility Study of Automatic Vertebra Segmentation Algorithm2020 ~ 2020MIRDC
    Using Ultrasonic Images to Identify and Locate Peripheral Nerves2018 ~ 2018MIRDC

    Students

    Students

      123(Grade 1)

    Honor & Awards

      International Conference